1. Open the Annihilate app on your mobile device to begin the game.

2. On the main screen, select a level to start playing.

3. Observe the puzzle grid where dynamic characters, called atoms, are placed.

4. Each atom has a specific color. Your goal is to match and eliminate pairs of atoms with the same color.

5. Swipe your finger in any direction—up, down, left, or right—or use keyboard arrows if available.

6. All atoms on screen will move simultaneously in the swiped direction until they hit an obstacle or the edge of the grid.

7. When two atoms of the same color touch, they annihilate and are removed from the board.

8. Plan your moves carefully, as the number of moves available is limited per level.

9. Watch out for obstacles such as lasers, black holes, and uranium 235. These can block your path or destroy atoms if not avoided.

10. Use walls and barriers strategically to align atoms without overshooting the target.

11. Complete the level by annihilating all matching atom pairs within the given move limit.

12. Progress to the next level, where new challenges and puzzles await.